Sal from the information you have provided if the basement area is unfinished then 220volt type nm or ser cables may be installed the same way electrical wiring is installed through an attic or crawl space as long as it is properly supported and protected.
Does 220v in attic require conduit.
The national electrical code which is the basis for all local building codes has specific regulations for installing electrical wires so that they are protected from damage.
A conduit that will be used for an electrical project must be approved for the application.
Spacing is a major factor in deciding whether to use conduit.
A favorite target of electrical inspectors is the improper use of non metallic cable nm in exposed locations such as basement foundation walls or along the face of studs and joists in unfinished framed spaces.
Uf cable can be direct buried without conduit with a minimum of 24 inches of earth cover.
Wiring buried inside rigid metal rmc or intermediate metal imc conduit must have at least 6 inches of earth cover.
The amount of wire fill inside any electrical conduit does not imply how many wires can be stuffed into the conduit but rather how many wires of the right type may be safely installed to prevent overheating of the electrical wiring.
Wiring in pvc conduit must have at least 18 inches of cover.
Several runs of wiring can be corralled with inexpensive cable stackers which maintain the distance mandated by code.
Does the wire need to be in conduit.
This is especially true when you need to curve the wires around a bend which further limits the space inside the conduit.
The volume of regulators inside the conduit is limited by code so it might not work to use conduit.